Daniel graduated with a first class honours degree, BSc in Physics with Medical Physics and Bioengineering from Dublin Institute of Technology. His final year research work involved the discrimination of fibroblast phenotypes using non-resonant Raman micro-spectroscopy and multivariate methods and was performed with Dr. Aidan Meade of the Radiation and Environmental Science Centre (RESC) in the Facility for Optical Characterisation and Spectroscopy (Focas) Research Institute in DIT.
During the third year of his undergraduate degree he spent time in the R&D Department of Bausch & Lomb Ireland where he worked as Student Process Development Engineer involved in the development of new products and the upkeep of current products. Primarily Daniel was involved in the early stage development of Biotrue™ for Presbyopia.
Role in the Project
Daniel joined the University of Dundee as a Marie Curie ESR fellow on the PHOtonic tools for Quantitative imaging in tissUeS (PHOQUS) project in July 2014 and is currently jointly supervised by Dr. Mike McDonald and Prof. Angus Lamond. His work will lead to the development of new technologies that will provide Fluorescence Lifetime Imaging Microscopy (FLIM) measurements with improved temporal and spatial resolution. In addition to enabling high contrast volumetric imaging the new technologies will have the potential to limit the effects of photobleaching and phototoxicity as is seen in conventional fluorescence microscopy modalities, hence improving biological applications including live cell imaging.
[November 2017] D2.5: Analysis of how chromatin compacts during cell division
[November 2017] D2.4: Measurement of chromatin condensation during mitosis
[December 2015] D2.2: Improved temporal resolution in FLIM-SPIM
Journal and Conference Papers and Posters
[September 2016] Light-sheet Fluorescence Lifetime Imaging. Oral presentation at PHOTON16, Leeds, UK, 7th September 2016.
[August 2016] Light-sheet Fluorescence Lifetime Imaging. Poster presented at the Biophotonic approaches: From molecules to living systems conference, Dundee, Scotland, 23rd August 2016.
[August 2016] Light-sheet Fluorescence Lifetime Imaging. Oral presention at the Biophotonic approaches: From molecules to living systems conference, Dundee, Scotland, 23rd August 2016.
August 2016] Polarised Light Sheet Tomography. Oral presentation at the Biophotonic approaches: From molecules to living systems conference, Dundee, Scotland, 22nd August 2016.
[June 2016] Light-sheet Fluorescence Lifetime Imaging. Poster presented at PHOTONEX SCOTLAND, Edinburgh, Scotland, 8th June 2016.
[May 2016] Polarised light sheet tomography, Sascha L. Reidt, Daniel J. O’Brien, Kenneth Wood, and Michael P. MacDonald. Optics Express Vol. 24, Issue 10, pp. 11239-11249 (2016). [OPEN ACCESS]